salk.gif (13330 bytes)


The following data constitutes irrefutable PROOF that Thomas Francis, Jr.'s polio vaccine study which justified the innoculation of 98% of Americans, one third of whom today exhibit the symptoms of the SV-40 virus, was a FLAGRANT FRAUD perpetrated on trusting American people:

  Total Children Polio Cases Cases Per 100k Paralytic per 100k Non-paralytic per 100k Doubtful Not Polio
Vaccine & Placebo 749,236 428 57.1 38.5 10.0 4.1 4.5
Control Sample 1,080,680 585 54.1        
Total 1,829,916 1,013 55.4        

What this data shows is that

Safe, effective, and potent."

With these words on April 12, 1955, Dr. Thomas Francis Jr., director of the Poliomyelitis Vaccine Evaluation Center at the University of Michigan School of Public Health, announced to the world that the Salk polio vaccine was up to 90% effective in preventing paralytic polio.

Dr. Francis made the announcement to a crowd of scientists and reporters at the University of Michigan's Rackham Auditorium, concluding his two-year national field trials of  the poliomyelitis vaccine developed by his former student, Jonas Salk. Francis was chair of the School of Public Health Department of Epidemiology where Salk did postgraduate training.

Over 1,800,000 children participated in the field trials, which were unprecedented in magnitude.

Links for more information:

University of Michigan Center for the History of Medicine:

Introductory Remarks by Jonas Salk at Field Trial Success Announcement, April 12, 1955:

International Polio Network: Polio and Post-Polio Fact Sheet

Text from first press release on polio vaccine evaluation results, April 12, 1955:

The University of Michigan Information and News Service
3564 Administration Building, Normandy 3-1511, ext. 2623
April 12, 1955


ANN ARBOR: The vaccine works. It is safe, effective, and potent.

Dr. Thomas Francis, Jr., UM Director of the Poliomyelitis Vaccine Evaluation Center, told an anxious world of parents that the Salk vaccine has been proved to be up to 80-90 percent effective in preventing paralytic polio.

At a meeting of over 500 scientists and physicians and before the penetrating eyes of cameras and powerful spotlights, Dr. Francis spoke on the effectiveness of the Salk vaccine. The meeting was held at the Rackham Auditorium in Ann Arbor under the joint sponsorship of the Rational Foundation for Infantile Paralysis and the University of Michigan.

Dr. Francis declared the vaccine had produced "an extremely successful effect" among bulbar-patients in the areas where vaccine and an inert substance had been tried interchangeably.

Financed by nearly one million dollars worth of dimes which have been donated to the National Foundation, the Francis Report may slow down what has become a double-time march of disease to a snail's pace.

In strong statistical language the historic trial of a vaccine and its subsequent analysis was revealed. Over 113 pages in length, the Report at long last called a halt to speculations and finally re-enforced laboratory findings with concrete field evidence. There can be no doubt now that children can be inoculated successfully against polio.

There can be no doubt that humanity can pull itself up from its own bootstraps and protect its children from the insidious invasion of ultramicroscopic disease.

For one thing what was feared turned out to be unfounded -- the vaccine proved incredibly safe. Reactions were nearly negligible. Only 0.4 percent of the vaccinated children suffered minor reactions. An even smaller percent (0.004-0.006) suffered so-called "major reactions."

And the persistence of protection appears reasonably good. When good antibody responses were obtained from vaccination, the report said "the effect was maintained with but moderate decline after five months."

Distribution of antibody levels among vaccinated persons was much higher than that in the control population from the same areas.

Out of a total population of 1,829,916 children a total of 1013 cases of polio developed during the study period and were reported to the Center.

In placebo control areas, where vaccine was interchanged with an inert substance, 428 out of 749,236 children contracted the disease.

In the observed control areas where only second graders were inoculated, 585 cases out of 1,080,680 children developed.

Percentages in the placebo areas were: 67.5 paralytic, 17.6 non-paralytic, 7.2 doubtful, and 7.6 not polio. Specifically, 33 inoculated children receaving the complete vaccination series became paralyzed in the placebo areas. This is opposed to 115 uninoculated children. Similarly, in the observed areas there were 38 such children who became paralyzed, as opposed to 330 uninoculated children.

There were four deaths among children who received placebo; none among the vaccinated. In observed areas there were 11 fatalities; none among children receiving the vaccine.

Only one child who had been inoculated with the vaccine died of polio, and this death followed a tonsillectomy two days after the second injection of the vaccine in an area where polio was already prevalent.

The Report also stated that in no area did Type II virus prevail. There was, however, prevalence in certain areas of Types I and III.

Marked sociological differences were noted by the U-M's Survey Research Center among the participating and non-participating children in the study. For example, there was a higher proportion of children participating who had been vaccinated against small-pox, diphtheria, and whooping cough than among the non-participants. Significant auxiliary findings were:


  1. The vaccine's effectiveness was more clearly seen when measured against the more severe cases of the disease;
  2. Although data were limited, findings in Canada and Finland support the Report in showing a significant effect of the vaccine among cases from whom virus was isolated
  3. Vaccination protected against family exposure. Only 1 out of 233 inoculated children developed the disease, while 8 out of 244 children receiving placebo contracted the disease from family contact.
  4. In picking the field trial areas, the National Foundation scored a major victory. Although in placebo areas cases were 27 per cent under the 1949-53 average, and 12 per cent less in the observed control areas, it was found that there had been a 26 per cent increase per 100,000 in trial areas as a non-trial areas. This meant that trial areas were appropriately selected for the best testing conditions for the vaccine.

The field trials and the evaluation were made possible by grants totalling $17,500,000 in March of Dimes Funds from the National Foundation for Infantile Paralysis.

horizontal rule

Thomas Francis Jr. and the polio Vaccine Field Trials


Thomas Francis Jr.
Thomas Francis Jr.


Dr. Thomas Francis Jr. (left), U.M. Director of the Poliomyelitis Vaccine Evaluation Center, was responsible for conducting the field studies of the Salk polio vaccine.

Dr. Jonas Salk, who created the vaccine, had the following words to say about Dr. Francis on the day of the polio announcement in 1955: "While many like to listen to music -- those who know how a musical score is put together can appreciate the creation of a theme from notes that to others of us are merely disconnected sounds. The unification of the diverse elements that have just emerged in a simple score, and yet so rich in overtones, could have been accomplished only by one of the great masters."


front cover of summary report of the field trials
Front Cover of Summary Report of the Field Trials


The Francis report was the culmination of a year-long field trial of the Jonas Salk vaccine, unprecedented in its scope and magnitude. Using a double-blind method of statistical analysis, where neither patient nor administering physician knew if the inoculation was the vaccine or a placebo, 440,000 children were given the vaccine and 210,000 the control substance. In addition Francis agreed to a controlled observation trial involving more than 1 million children, participating either as knowing recipients of the Salk vaccine or as non-inoculated children placed under observation for comparison. All told approximately 1,830,000 children in 217 areas of the United States, Canada, and Finland were involved in the field trial.

As a statistical exercise, the polio field trial was unique in the annals of epidemiological study. Here is just one example of the enormity of the work accomplished by Francis and the Polio Vaccine Evaluation Center. In that era of key-punch cards, Francis and his staff at the University of Michigan produced some 1,800,000 IBM punch cards containing 144,000,000 pieces of information about the test children.

On staff at the Evaluation Center was a small army of statisticians, epidemiologists, and clerical and support personnel. This latter group of more than 100 individuals was responsible for tabulating the data received from public health officials and doctors in the field who were participating in the study. According to University press releases, more than 300,000 individuals participated in the field trials; 20,000 physicians and public health officers, 40,000 registered nurses, 14,000 school principals, and 200,000 volunteer workers.

--Thomas Powers, Bentley Historical Library Exhibit, 1994